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As the United States University Of Cincinnati T-Shirt . inches closer to authorizing a Covid-19 vaccine many people may now let themselves start wondering what it will feel like to get it. Is it going to be like the flu vaccine? Will it be more painful? And what about side-effects? The two front-runners for getting an emergency use authorization from the US Food and Drug Administration — Pfizer/BioNTech and Moderna — use new mRNA technology. No US-licensed vaccine has ever used it, although researchers have been studying it for decades, against infections like flu, rabies and Zika, and even for some types of cancer. The way these mRNA vaccines work is that they give our body the instructions, in the form of messenger RNA, for making a little piece of this particular coronavirus (SARS-CoV-2) — specifically the spike protein. When our body gets these instructions, it starts producing the spike protein. That in turn triggers our immune system, which recognizes the spike protein as “foreign,” to make antibodies against it. So when we get infected with the real virus, our body is already prepared to fight it.
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These vaccines require two doses: one to prime the body, and then a few weeks later, a second shot to boost the response University Of Cincinnati T-Shirt . Study results show that Pfizer/BioNTech and Moderna’s vaccines are each in the neighborhood of 95% effective. But because the technology is so new for a vaccine, it has raised many questions and some concerns among those for whom it’s intended. One participant in the Moderna trial said getting vaccinated was “definitely not a walk in the park” but he would certainly do it over again. Yasir Batalvi, a 24-year-old recent college graduate living in the Boston area, said he originally signed up to join a trial on the NIH website back in early July because he felt moved to do something to help during the pandemic. “I felt so helpless. I mean, this pandemic really has affected everybody’s lives so significantly. And it’s not just lives, you know, it’s livelihoods,” Batalvi told CNN Chief Medical Correspondent Dr. Sanjay Gupta. “And so I signed up because I kind of just wanted to do what I could. And I didn’t think I was necessarily going to get picked. But I got a call, eventually, in September. And then by mid-October, I was enrolled.” He was a bit nervous rolling up his sleeve, especially when he was given a 22-page consent form to sign. But he said he felt like he was doing a public service. “I think just because coronavirus has been such a significant disruption to our lives, that I decided that it was what I had to do. It felt like civic duty,” he said. “Because I think mass scale vaccination is really the only realistic way out of the pandemic that we’re in.”
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